abstract：:Hereditary optic nerve disorders are rare. For ophthalmologists, Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are of particular relevance. LHON and ADOA are diseases of the retinal ganglion cells and are caused by mitchochondrial dysfunction. LHON is based on mutations of the ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Rüther K

更新日期：2018-06-01 00:00:00

abstract：:Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramp...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Wabbels B

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Advanced cataract with hard lens nuclei frequently challenge the ophthalmologic surgeon when doing phacoemulsification. In the present study, we examined the effect of a new phaco tip design during cataract surgery. PATIENTS AND METHODS:100 patients were assigned to two groups. In group 1 (50 patients), the...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Vetter JM,Wirbelauer C

更新日期：2018-05-01 00:00:00

abstract：:Biologic disease modifying antirheumatic drugs (bDMARDs) can be highly efficient in the treatment of various non-infectious uveitis entities. Currently, the TNF-α-inhibitor Adalimumab is the only in-label therapeutic option, whereas, all other bDMARDs need to be given as an off-label therapy. bDMARDs are indicated in ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Walscheid K,Pleyer U,Heiligenhaus A

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The foveo-papillary angle (FPA) on fundus photographs is the accepted standard for the measurement of ocular cyclotorsion. We assessed the inter-rater reliability of this method in healthy subjects and in patients with trochlear nerve palsies. PATIENTS AND METHODS:In this methodological study, fundus photog...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Dysli M,Kanku M,Traber GL

更新日期：2018-04-01 00:00:00

abstract：:In everyday practice, intravitreal therapy in an "as needed" regimen (pro re nata, PRN) is less predictable and requires more visits (monitoring and injections taken together) with poorer functional results than with the treat and extend (T&E) regimen. Current literature supports the benefit of a switch. However, prac...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Imesch P,Sarra GM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:With a cooperative patient, examination of the optic nerve head using optical coherence tomography (OCT) is fast and easy to perform and facilitates identification and monitoring of different pathological changes in the optic nerve head. MATERIALS AND METHODS:Characteristic findings and scanning options are...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Unterlauft JD,Tegetmeyer H

更新日期：2018-01-01 00:00:00

abstract：:Optical coherence tomography (OCT) enables noninvasive high-resolution 3D imaging of the human retina, and thus plays a fundamental role in ophthalmology. Via OCT examination, even subtle retinal changes can be captured, which occur in very early stages of different diseases (e.g., glaucoma, diabetes mellitus, or age-...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Röhlig M,Jünemann A,Fischer DC,Prakasam RK,Stachs O,Schumann H

更新日期：2017-12-01 00:00:00

abstract：:Background Until now, many studies have investigated the link between motor development and visual-spatial abilities in infancy and childhood. Most of these studies found evidence that there is such a link in typically developing children or children with locomotor delay. Only a few studies have tested the consequence...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Dillmann J,Freitag C,Holve K,Schweinfurth S,Lorenz B,Schwarzer G

更新日期：2017-10-01 00:00:00

abstract：:Purpose OCT-A is a new method to visualise the 2D and 3D structures of neovascular complexes in exudative AMD. The aim of the present study was to characterise type 2 CNV in different 2D segmentations and in 3D imaging and to investigate changes during anti-VEGF treatment. Methods 12 patients with type 2 CNV in FA and...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Faatz H,Rothaus K,Gunnemann F,Gutfleisch M,Heimes-Bussmann B,Lommatzsch A,Pauleikhoff D,Farecki ML

更新日期：2017-09-01 00:00:00

abstract：:Background The introduction of VEGF inhibitors revolutionized treatment for age-related macular degeneration. However, it requires regular intravitreal (IVT) injections. Hence, replacement of IVT injections by topical, non-invasive eye drop treatment is subject to intensive research. Material and Methods Literature an...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Zeitz O,Joussen AM

更新日期：2017-09-01 00:00:00

abstract：:Recent technological innovations in cataract surgery have made the procedure even more precise and safe and the odds of having a highly satisfied patient even higher. These innovations include visualisation systems - such as intraoperative aberrometry - which are particularly helpful when it comes to implanting toric ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Dick HB,Schultz T

更新日期：2017-08-01 00:00:00

abstract：:Background The aim of this retrospective study was to evaluate the rotational stability and the refractive outcome of two different toric IOLs. Methods This study included 41 eyes with corneal astigmatism greater than 1.5 diopters (D). All patients underwent surgery in the Department of Ophthalmology at Hietzing Hospi...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Grohlich M,Miháltz K,Lasta M,Weingessel B,Vécsei-Marlovits V

更新日期：2017-06-01 00:00:00

abstract：:Correct differential diagnosis in cases of blurred optic disc margins is a challenging task for ophthalmologists. The reliable differentiation of pseudopapilloedema and true papilloedema has significant implications for proper patient management. Conditions that give rise to pseudopapilloedema include small crowded di...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Biermann J,Lagrèze WA

更新日期：2017-06-01 00:00:00

abstract：:A solar eclipse is an impressive natural phenomenon that was last experienced in Europe in 2006. Last year, on March 20th 2015, a solar eclipse was visible in much of Europe. Solar retinopathy is a recognised potentially sight threatening condition that has been associated with direct or unprotected sun gazing. Public...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Tsatsos M,MacGregor C,Gousia D,Moschos M,Detorakis E

更新日期：2017-06-01 00:00:00

abstract：:Background Eyes with severe corneal opacifications and insufficient prognosis for high-risk corneal transplantation can be considered for the implantation of a Boston-keratoprosthesis. Since 2013, this technique of "artificial" corneal replacement is provided to high-risk eyes at the Department of Ophthalmology, Unive...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Schaub F,Bachmann BO,Seyeddain O,Moussa S,Reitsamer HA,Cursiefen C

更新日期：2017-06-01 00:00:00

abstract：:Background "En face" optical coherence tomography (OCT) is an imaging technique with optic sections parallel to the retinal pigment epithelium (RPE). This study aims to define the use of this technique in the evaluation of small pigmented choroidal tumors. Patients and Methods Investigation of 27 small pigmented choro...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Cotting-Bodmer S,Zografos L,Schalenbourg A

更新日期：2017-04-01 00:00:00

abstract：:Background To evaluate the technique of inverted internal limiting membrane (ILM) flaps for the management of large macular holes and autologous ILM free flaps for non-closing macular holes. Patients and methods All macular holes were treated with pars plana vitrectomy and dual blue assisted ILM flap technique. The in...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Guber J,Lang C,Valmaggia C

更新日期：2017-04-01 00:00:00

abstract：:The use of adaptive optics in ophthalmoscopy is a breakthrough technological achievement. With AO ophthalmoscopes, the microscopic retinal structure can be visualised non-invasively and on a cellular level, allowing for cellular scale imaging of the retinal nerve fibre layer, the smallest retinal capillaries, rod and ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Reiniger JL,Domdei N,Pfau M,Müller PL,Holz FG,Harmening WM

更新日期：2017-03-01 00:00:00

abstract：:Critically ill patients in the intensive care unit (ICU) may develop eye problems, due to impaired ocular protective mechanisms or direct involvement of the eye in severe systemic diseases. If eye infections or ocular surface disorders are not identified in time, endophthalmitis or corneal ulcer may develop and can ca...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Siebert C,Menges A,Tost FH

更新日期：2017-01-01 00:00:00

abstract：:In ophthalmology, regenerative medicine is rapidly becoming a reality. Cell based treatment strategies in end stage retinal degeneration may be of therapeutic value, whatever the mechanism of disease mechanism. However, while corneal transplantation is commonly performed with excellent results, many obstacles must be ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Seitz IP,Achberger K,Liebau S,Fischer MD

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Data from real-life studies on neovascular AMD (nvAMD) generally fall significantly behind respective data from interventional prospective trials. This can be attributed at least partially to differences in patient cohorts concerning both stages of AMD (including consecutive scarring or atrophy), as well as ...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Sachs HG,Wilke RG

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the duration of the preoperative examination and patient comfort in measurements with an Image Guided System (Verion, Alcon), which is used for the calculation and intraoperative alignment of toric intraocular lenses, in comparison to established keratometry devices. PATIE...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Thomas BC,Müller A,Auffarth GU,Holzer MP

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:The first Oskar Fehr lecture is given in honour of Professor Fehr, a well respected ophthalmologist, who was head physician of the Department of Eye Diseases at the Rudolf Virchow Hospital from 1918. He practiced there until 1938, when he was forbidden to enter the clinic because he was Jewish and subject to th...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Weiss JS

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of an intravitreal dexamethasone implant (Ozurdex®) in patients with cystoid macular oedema (CME) suffering from non-infectious uveitis. METHODS:Monocentric, retrospective, single-arm analysis in 49 patients (59 implanted eyes) with inactive uveitis, in whom CME had been unresponsive t...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Breitbach M,Rack D,Dietzel M,Heinz C,Heiligenhaus A

更新日期：2016-05-01 00:00:00

abstract：:Purpose. The aim of this pharmacogenetic study was to evaluate the impact of high-risk alleles in factor H, factor C3 and vascular endothelial growth factor (VEGF) on the response to intravitreal bevacizumab in patients with neovascular age-related macular degeneration (AMD) in a Tunisian population. Methods. Ninety p...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Habibi I,Kort F,Sfar I,Chebil A,Bouraoui R,Ben Abdallah T,Gorgi Y,El Matri L

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In the city of Zurich, vision screening is performed by school medical services as part of the legally compulsory preventive medical examinations. We retrospectively evaluated the results of the 2011-2012 school year. PATIENTS AND METHODS:Preventive medical examinations by the school medical services were p...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Sturm V,Heckmann J,Wandernoth P,Kunz A,Steffen T,Schmitt Oggier S

更新日期：2016-04-01 00:00:00

abstract：:Optic disc drusen are an important differential diagnosis in the diagnostic evaluation of a prominent optic nerve head. Drusen of the optic disc occur in 0.34 to 2.4 % of human individuals and manifest themselves bilaterally in three of four cases. Drusen are found six times more often within histological sections tha...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Nentwich MM,Maertz J,Rudolph G

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Little is known about how the expression of Ephrin type-A receptor 2 (EphA2) influences cell-cell adhesion, migration, angiogenesis, and the formation of vasculogenic mimicry (VM) channels in uveal melanomas or how this may be related to the rate of metastasis. MATERIAL AND METHODS:Paraffin embedded section...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Vukoja V,Brandenbusch T,Tura A,Nassar K,Rohrbach DJ,Lüke M,Grisanti S,Lüke J

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The goal of glaucoma treatment is to maintain the patient's visual function and related quality of life, at a sustainable cost. In this review, methods of measuring quality of life are presented, together with their impact in clinical practice. METHODS:Searches were from the inception of the database to dat...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Hirneiss C,Kortüm K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Additive manufacturing and 3D printing create new paths for the design and manufacturing of implants. Technologies with high resolution are required for the development of microstructured eye implants. In the present study, we demonstrate how these technologies can be used during the design development and m...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Hinze U,El-Tamer A,Reiß S,Stolz H,Guthoff R,Stachs O,Chichkov BN

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:To examine the differences in intraocular pressure (IOP) measurements obtained with Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (DCT) in subjects with thin corneas and to correlate these with structural and functional parameters of glaucoma damage. PATIENTS AND METHODS:One hund...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Umurhan Akkan JC,Akkan F,Sezgin Akcay BI,Ayintap E,Tuncer K

更新日期：2015-10-01 00:00:00

abstract：:Für die (Früh-)Diagnose einer Glaukomerkrankung ist die Beurteilung der Papille von entscheidender Bedeutung. Das Spektrum von High-Tech-Geräten zur Papillenbeurteilung hat sich in den letzten Jahren erweitert und die Anwendung ist in der klinischen Praxis angekommen 1. Voraussetzung für die sinnvolle Anwendung und In...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Budde WM

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:An evaluation of the visual and refractive results was undertaken one year after implantation of a trifocal diffractive toric intraocular lens (IOL) during cataract surgery. METHODS:In a prospective study patients with a calculated postoperative corneal astigmatism of ≥ 0.75 D received a diffractive trifocal t...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Höhn F,Tandogan T,Breyer DR,Kaymak H,Hagen P,Klabe K,Koss MJ,Gerl M,Auffarth GU,Kretz FT

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Proliferative retinopathy is an important cause of vision loss in diabetic patients. Incomplete panretinal photocoagulation (PRP) can lead to recurrent proliferation of new vessels. PATIENTS AND METHODS:We retrospectively analysed the outcome of patients with high risk proliferative diabetic retinopathy (PD...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Ambresin A,Strueven V,Pournaras JA

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:In order to obtain artifact-free electro-oculogram recordings the subject's cooperation is necessary. The aim of our study is to evaluate the recording characteristics of short-duration EOG and to compare the effect of mydriasis on electro-oculogram recordings in a cohort of controls. PATIENTS AND METHODS:E...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Türksever C,Orgül S,Todorova MG

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Laser peripheral iridotomy is a useful method in primary angle-closure eyes to prevent angle-closure attack and development of glaucomatous optic nerve damage. The aim of this study was to quantify morphological changes after LPI and their impact on intraocular pressure, and to evaluate predictive parameters...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Nützi C,Orgül S,Schötzau A,Grieshaber MC

更新日期：2015-04-01 00:00:00

abstract：:Die Tränendrüse kann von einer Vielzahl neoplastischer, infektiöser und autoimmunologischer Erkrankungen betroffen sein. Eine radiologische Charakterisierung der Veränderungen kann Hinweise für die differenzialdiagnostische Einordnung liefern. Erkrankungen der ableitenden Tränenwege, insbesondere Tränenwegsverschlüsse...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Pieper CC,Thomas D

更新日期：2015-03-01 00:00:00

abstract：:Patients suffering from various retinal diseases benefit from therapies directed against the vascular endothelial growth factor (VEGF). Aflibercept (Eylea) is another VEGF-binding protein available for intravitreal injection, in addition to the antibody bevacizumab (Avastin) and the F(ab) fragment ranibizumab (Lucenti...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Lang GE,Lang GK,Deissler HL

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the long-term success rates of a multimodal concept for treating functional nasolacrimal duct obstruction (FNLDO) consisting of minimally invasive lacrimal duct surgery and additional treatment of the conjunctiva, the puncta or the lids if necessary. METHODS:Clinical outco...

journal_title：Klinische Monatsblatter fur Augenheilkunde

authors： Stemplewitz B,Amin S,Emmerich KH,Gesser-Wendt C,Meyer-Rüsenberg HW

更新日期：2015-01-01 00:00:00